Cleveland beat the Yankees by the most lopsided of scores, 19-1, on of all days the Boss's birthday. Oddly, it is not the most lopsided game in their history. The Indians beat the Yankees by 22 runs once (22-0) on August 31, 2004 and by 18 one other time (24-6 on July 28, 1929). The Yankees' largest margin of victory against the Indians was 20 runs (21-1 on July 24, 1999) and they hit 18 twice (21-3 on July 14, 1904 and 18-0 on July 10, 1936).

It was just the fifth time that the Indians had won a game by 18 runs or more at home in their history and the first in over 56 years. Here they are by margin of victory:

The loss matches Yankees worst on the road, the July 29, 1928 game against Cleveland above.

As for the most lopsided victories of all time, this one only ranks at 286th. The most lopsided game in baseball history was June 18, 1874 when the New York Mutuals topped the Chicago White Stockings (now the Cubs), 38-1. Here are the most lopsided ever by margin of victory:

You'll note that a lot of these come from the early days of major-league baseball. Barring nineteenth century games, here are the most lopsided: